Herein, we performed the validation of the polycationic phosphorus dendrimer-based approach for small interfering RNAs delivery in cancer stem cell in vitro. As a molecular…
The failure of a long-lasting curative therapeutic benefit of currently applied chemotherapies against malignant cancers is suggested to be caused by the ineffectiveness of such…
Limitations in genetic stability and recapitulating accurate physiological disease properties challenge the utility of patient-derived (PD) cancer models for reproducible and translational research. A portfolio…
Our computational pipeline constructed a gene signature that enables us to predict clinical prognostic value of hitherto unrecognized biomarkers for PAAD. Sensory ion channels TRPC3…
Background: Lack of reproducibility in preclinical research is a problem posing ethical and economic challenges for biomedical science. Various institutional activities from society stakeholders of…
Redox regulation of specific cysteines via oxidoreductases of the thioredoxin family is increasingly being recognized as an important signaling pathway. Here, we demonstrate that the…
Collaborative paper with Margriet Ouwens, German Diabetes Center Düsseldorf and Or Kakhlon, Hadassah Medical Center in Jerusalem identifying the cardinal role of canonical WNT signaling…