All news are regularly updated on our institutional homepage
The news feature on our institution homepage gives up to date updates on new developments at MES.
Science meets business
Thanks Alex for igniting the business envelop. Exited for this journey to come...
Student evaluation
The Erasmus Programm ("EuRopean Community Action Scheme for the Mobility of University Students") is a European Union (EU) student exchange program established in 1987. Erasmus+,…
Nomination in scientific society
Ulf Kahlert was nominated in another scientific Society, this time as a full member into Sigma Xi, The Scientific Research Honor Society (Well Cornell, USA).…
James Lu- foreign member of Academia Europaea visits our lab
It was a great honor to host James Lu in our lab. New cooperation projects have been initiated and coordinated programs for strategic staff exchanges…
2023 – 14 publication, 92 total Impact factor points
In the year 2023 our lab has published 14 papers with a total Impact of 92 points. Academic exploitation of our research is one of…
Invited talk
As the world counts down to the 2030 deadline of the UN agenda, major economies like China and Germany are encountering common challenges, which call…
Local media press release about blood test for detection of pancreatic cancer
Our work on early detection of pancreatic cancer in patients blood raised public interest. We continue to thrive for better future care for patients and…
New publication on transcriptional classification of breast cancer susceptibility to immune therapy
A chromatin regulator-related gene signature was calculated, and this signature provides the strong independent predictive capability for clinical prognosis and immunotherapy efficacy for patients …
New publication on blood-based molecular stratification of pancreatic cancer
In a collaboration between the partner sites Heidelberg and Dresden of the National Center for Tumor Diseases (NCT) a blood extracellular-vesicle-transported mRNA signature to discriminate…
Cancer Neuroscience
As part of the NEURO-ONCOLOGY WORKING GROUP (NOA) in the German Cancer Association (DKG) we had the pleasure to moderate a webinar on fundamentals, current…
New publication on immune therapy against MYC-driven malignancy
The findings suggest a dynamic relationship between MYC amplification and innate immune suppression in MYC amplified neoplasms and support further investigation of phagocytosis modulation as…
New Membership
Accreditation approved to participate in European network on 3R - Replace, Refine, Reduce animal research. Excited to participate in WG1 on "Quality and Translatability of…
New publication on MET alterations informing on therapy sensitivity
MET F/SVs but not genomic amplification, were highly enriched in the secondary glioblastomas (sGBM) and marked worse prognosis. Further molecular and scRNA-seq analysis revealed that…
“All THIS MESS: checking validity in clinical studies.”
Data Prevalence is defining co-founder in statistics. Thanks for your visit Dr. Klimova from NCT partner site Dresden.
Invited talk
November 2022: Invited talk at NOA Annual Meeting in Kopfklinik University Medical Center Heidelberg. Interesting to learn about the Alcatraz concept of cancer therapy.
Invited talk
October 2022: Invited talk Nano2Clinic Final conference @ La Sapienza, Rome. Great progress towards position paper on innovation for future drug development and new COST…
New publication
New publication with participation of our team on the transcription factor ZEB1 and its potential as therapeutic target in neuroinflammatory diseases.
New publication
New publication from your team on Collagen 10 type A1 and its relevance as clinical predictive marker in colon cancer.
Inauguration rector H2
Inauguration celebration for Manuela Schwartz. Interesting gathering of representatives from research, funding organization, religion, politics and art! Best of success and luck with decisions in…
Viszeralmedizin 2022
Viszeralmedizin 2022 in Hamburg, transdisciplinary forum updates on current developments in clinical and translational R&D for new treatments and diagnostics of gastrointestinal and hepatobiliary diseases.…
Tech Transfer Show
Technology Transfer Show Saxony-Anhalt 2022, interesting products spun out from academic centers in the state, incl. from our cooperation partners @ STIMULATE on new MR…
Optimizing tumor tissue acquisition from the surgical operation room
Insightful and productive trans-disciplinary working session with the nursing team of the general surgery operation room. MES administration and technical staff discussed procedures to optimize…
STIMULATE research campus
Image-guided cancer therapy - interesting to learn about the progress of work at the labs of Borna Relja, Heike Walles and Sylvia Saalfeld during the…
Potluck
MES shared some culinary highlight-moments and inspiring discussions over Mirza Ghasemi, Obastzta and Pisco Sour (or Pisco pure ;) ) with our friends from HealthTEC…
Serving the European Research Community
We spent some of our the summer time reviewing grant proposals from various funding organizations in Europe... Poland (National Science Center), France (Institut National Cancer),…
Lab Out 2022 – Canoeing on River Elbe
With 33 degrees Celsius, we enjoyed a refreshing breeze on a day out of the lab on the water of the River Elbe. Our tour…
Belgian waffles
Middle of July, resident doctor and current MES member Frederike Weber celebrated her successful doctoral graduation (back in her former home university Göttingen) providing a…
Expression signature of ECM genes predicts clinical course of patients suffering of deadly cancer
We have described the hitherto unrecognized potential of elevated expression levels of certain extracellular matrix (ECM) genes in brain tumor tissue to be of predictive…
Too low quality standards of reporting practices in scientific literature in in vitro cancer research
Finally our systematic review and meta-analysis on publication practices in scientific literature of a selected area of in vitro cancer research is out (it took…
Drug development: Establishment of new gene-therapeutics candidate belonging to the class of polycatisonic phosphorus dendrimer
Herein, we performed the validation of the polycationic phosphorus dendrimer-based approach for small interfering RNAs delivery in cancer stem cell in vitro. As a molecular…
Drug development: Synthesis of a new stem cell-directed, anti-metabolic drug
The failure of a long-lasting curative therapeutic benefit of currently applied chemotherapies against malignant cancers is suggested to be caused by the ineffectiveness of such…
Publication: Development of synthetic human cancer stem cell platform
Limitations in genetic stability and recapitulating accurate physiological disease properties challenge the utility of patient-derived (PD) cancer models for reproducible and translational research. A portfolio…
Signal transmitting neuron or nerve cell- 3d illustration
New publication on “sensory ion channel” as a biomarker for clinical course in PDAC
Our computational pipeline constructed a gene signature that enables us to predict clinical prognostic value of hitherto unrecognized biomarkers for PAAD. Sensory ion channels TRPC3…
New original research paper suggesting a formula how to minimize the risk of elevated heterogeneity of in vitro research
Background: Lack of reproducibility in preclinical research is a problem posing ethical and economic challenges for biomedical science. Various institutional activities from society stakeholders of…
New co-authored publication on redox signaling
Redox regulation of specific cysteines via oxidoreductases of the thioredoxin family is increasingly being recognized as an important signaling pathway. Here, we demonstrate that the…
New publication on WNT signaling
Collaborative paper with Margriet Ouwens, German Diabetes Center Düsseldorf and Or Kakhlon, Hadassah Medical Center in Jerusalem identifying the cardinal role of canonical WNT signaling…