Belgian waffles
Middle of July, resident doctor and current MES member Frederike Weber celebrated her successful doctoral graduation (back in her former home university Göttingen) providing a…
Expression signature of ECM genes predicts clinical course of patients suffering of deadly cancer
We have described the hitherto unrecognized potential of elevated expression levels of certain extracellular matrix (ECM) genes in brain tumor tissue to be of predictive…
Too low quality standards of reporting practices in scientific literature in in vitro cancer research
Finally our systematic review and meta-analysis on publication practices in scientific literature of a selected area of in vitro cancer research is out (it took…
Drug development: Establishment of new gene-therapeutics candidate belonging to the class of polycatisonic phosphorus dendrimer
Herein, we performed the validation of the polycationic phosphorus dendrimer-based approach for small interfering RNAs delivery in cancer stem cell in vitro. As a molecular…
Drug development: Synthesis of a new stem cell-directed, anti-metabolic drug
The failure of a long-lasting curative therapeutic benefit of currently applied chemotherapies against malignant cancers is suggested to be caused by the ineffectiveness of such…
Publication: Development of synthetic human cancer stem cell platform
Limitations in genetic stability and recapitulating accurate physiological disease properties challenge the utility of patient-derived (PD) cancer models for reproducible and translational research. A portfolio…